I use cutting-edge genomic technologies to understand the impact of human genetic variation and to understand the genetic causes of musculoskeletal disease

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Rare Variant Associations

Since 2009, I have been working to understand the impact of rare genetics variants, both coding and non-coding on complex traits. Read more →

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Common Variant Associations

Using genotyping microarrays and exome sequencing, we have identified a number of variants associated with clubfoot and adolescent idiopathic scoliosis. Read more →

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High-Throughput Mutagenesis

 We have developed a method of high-throughput mutagenesis to enable high-throughput functional assessment of genetic variation. Read more →

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Epidemiology of AIS

We are interested in uncovering measurable factors that correlate with AIS risk or severity. To that end, we measure traits common in AIS patients and have developed disease and severity risk scores based on these traits. Read more →